“Wertbestimmungen – Evaluations” Standardising Therapeutic Agents 1890-1950 Drug Trajectories IV

A conference organised by Christoph Gradmann, University of Heidelberg, Institute for the History of Medicine, 4./5.march 2005

In collaboration with the Joint Research Group History of Therapeutic Agents in France and Germany (http://misha3.u-strasbg.fr/jrg-ta/)

Conference theme: Starting around 1890, the development, production and application of preventive and therapeutic vaccines became an important feature of medicine and the life sciences. The co-operation between pharmaceutical companies, academic researchers, clinicians, and public health officials can be seen as an early example of 20th-century biotechnology. Standardisation introduced for the purpose of controlling the efficacy of therapeutic agents became a distinctive feature of 20th century medicine. Starting from the historical origins of such practices which can be found in Paris and Berlin around 1890 the conference will look at some examples from the 20th century to explore the importance and diversity of such processes.

__________________________________________________ “Wertbestimmungen – Evaluations” Standardising Therapeutic Agents 1890-1950 Heidelberg 4th / 5th March 2005

Drug Trajectories 4

Friday, 4.3., 10 am Christoph Gradmann (Heidelberg): Introduction

1st group, 10.30 am to 12.30 am Cay-Ruediger Pruell (Freiburg): The Comeback of a Physician. Paul Ehrlich, Wertbestimmung and Sera Standardisation Michael Worboys (Manchester): The Wright Way: The Production and Use of Therapeutic Vaccines in Britain, 1902-1914 Pauline Mazumdar (Toronto): The state, the Serum Institute and the League of Nations

2nd group, 2 pm to 6 pm Gabriel Gachelin (Paris): Anti-diphtheria serum-therapy at the Institut Pasteur:

a empirical normalization? Mariama Kaba (Lausanne): “A Geneve on a de la excellent serum!” Autonomy and isolation in Swiss cantons during the first years of Diphtheria serum use: the Geneva case study Axel Huentelmann (Berlin): Evaluation and standardisation as a practical technique for administration. The example of the diphtheria serum Jonathan Simon (Berlin): Monitoring the Stable at the Pasteur Institute

Saturday 3rd group, 9 am to 12.30 am Anne Hardy (Heidelberg): From Diphtheria to Tetanus. The Development of Evaluation Methods for Sera in Imperial Germany Anne-Marie Moulin (Kairo): Circulating vaccines in the Pastorian network Delphine Berdah (Paris): Standardization of vaccines against foot-and-mouth disease: protecting cattle or economy? Ulrike Lindner (München): Different national responses to the implementation of Inactivated Polio Vaccine(IPV) in West Germany and the UK

4th group 2 pm to 6 pm Christian Bonah (Strassbourg): “We need for digitalis preparations what the state has established for serumtherapy …” From collecting plants to international standardization: the strophantin case, 1900-1935. Jean-Paul Gaudilliere (Paris): The visible industrialist: therapeutic potency, biological assays and the standardization of the sex hormones Christiane Sinding (Paris): From drug standardization to drug regulation: the case of insulin Gabriele Moser (Freiburg): “Serotherapy for Cancer”: Methods of Serological Diagnosis and their Evaluation in the Tumor Research Programme of the Germany Federal Research Council (DFG), 1930ies Alberto Cambrosio (Montreal): Commentary

If you are interested in attending or want some more information please contact Christoph Gradmann at [email protected]